Forced swim stressor: Trends in usage and mechanistic consideration
نویسندگان
چکیده
منابع مشابه
Coping with the Forced Swim Stressor: Towards Understanding an Adaptive Mechanism
In the forced swim test (FST) rodents progressively show increased episodes of immobility if immersed in a beaker with water from where escape is not possible. In this test, a compound qualifies as a potential antidepressant if it prevents or delays the transition to this passive (energy conserving) behavioural style. In the past decade however the switch from active to passive "coping" was use...
متن کاملThe mouse forced swim test.
The forced swim test is a rodent behavioral test used for evaluation of antidepressant drugs, antidepressant efficacy of new compounds, and experimental manipulations that are aimed at rendering or preventing depressive-like states. Mice are placed in an inescapable transparent tank that is filled with water and their escape related mobility behavior is measured. The forced swim test is straigh...
متن کاملEvaluation of antidepressant activities of rose oil and geranium oil in the forced swim test in mouse
Depression is one of the most common psychiatric disorders that may result in significant consequences in active population of the society. In traditional manuscripts there are many indications about the antidepressant effects of rose oil, but so far no scientific research has been done about this subject. The purpose of present study was to determine the antidepressant effects of rose oil and ...
متن کاملBiological Factors Influencing the Mice Forced Swim Test
The forced swim test (FST), originally developed by Porsolt et al., is highly valuable for assessing the antidepressant-like effects of the majority of currently-available antidepressants. Lucki et al. modified some parameters of the traditional FST in order to facilitate the differentiation between serotonergic and noradrenergic classes of antidepressant drugs. In addition, the FST is one of t...
متن کاملEvaluation of antidepressant activities of rose oil and geranium oil in the forced swim test in mouse
Depression is one of the most common psychiatric disorders that may result in significant consequences in active population of the society. In traditional manuscripts there are many indications about the antidepressant effects of rose oil, but so far no scientific research has been done about this subject. The purpose of present study was to determine the antidepressant effects of rose oil and ...
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ژورنال
عنوان ژورنال: European Journal of Neuroscience
سال: 2021
ISSN: 0953-816X,1460-9568
DOI: 10.1111/ejn.15139